Application Aspects of Animal and Human Mitochondrial Genomics

نویسندگان

  • Brygida Ślaska
  • Alexander Makarevič
  • Magdalena Surdyka
  • Sylwia Nisztuk
چکیده

Currently, extensive investigations are being carried out in the area of mitochondrial genomics. Mitochondrial DNA is used in many fields of science, e.g. evolutionism, phylogeography, anthropology, archaeology, forensics, medical diagnostics, veterinary medicine, molecular ecology, population genetics, and animal breeding. Mitochondrial markers, haplotypes, or haplogroups are associated with pathogenesis of diseases, evolution and origin of organisms, and identification of species. An interesting direction based on mitochondrial DNA sequences is the research into polymorphisms/mutations that can be related to economically important utility traits of livestock. The use of mtDNA has drawbacks due to the low power of discrimination and pattern of inheritance. Still, mtDNA has many advantages as a marker; therefore, it is often used in both basic and applied research.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ancient DNA from Human and Animal

Research on ancient DNA (aDNA) has the potential to enable molecular biologists and archeologists to decipher certain aspects of history by direct looking into the past. However, several major problems in this field limit the applicability of aDNA studies, most importantly contamination with modern DNA and postmortem DNA degradation. In this study we extracted and analyzed aDNA obtained from ~3...

متن کامل

Genome Wide Association Studies, Next Generation Sequencing and Their Application in Animal Breeding and Genetics: A Review

Recently genetic studies have been revolutionized by next generation sequencing (NGS) technology, and it is expected that the use of this technology will largely eliminate defects in the methods of association studies. The NGS technology is becoming the premier tool in genetics. However, at the moment the use of this method is limited especially in the livestock due to high cost and computation...

متن کامل

Mitochondrial DNA variation, genetic structure and demographic history of Iranian populations

In order to survey the evolutionary history and impact of historical events on the genetic structure of Iranian people, the HV2 region of 141 mtDNA sequences related to six Iranian populations were analyzed. Slight and non-significant FST distances among the Central-western Persian speaking populations of Iran testify to the common origin of these populations from one proto-population. Mismatch...

متن کامل

Trend of toxocariasis in Iran: a review on human and animal dimensions

One of the neglected soil and/or food-borne diseases with international public health importance is toxocariasis. Human cases are being increasingly reported from Asian, African, Oceania, European and the American countries. Hence, human toxocariasis (HT) is now considered as a major zoonosis with global and regional importance. In Iran, human and animal toxocariasis is an endemic disease with ...

متن کامل

Application of Next-generation Sequencing Technology in Forensic Science

Next-generation sequencing (NGS) technology, with its high-throughput capacity and low cost, has developed rapidly in recent years and become an important analytical tool for many genomics researchers. New opportunities in the research domain of the forensic studies emerge by harnessing the power of NGS technology, which can be applied to simultaneously analyzing multiple loci of forensic inter...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014